Article
Genes and coronary artery disease: where are we?
Journal of the American College of Cardiology - 30 Oct 2012
Roberts Robert, Stewart Alexandre F R
Abstract excerpt
Susceptibility to coronary artery disease (CAD) is claimed to be 40% to 60% inherited, but until recently genetic risk factors predisposing to CAD have been elusive. Comprehensive prevention of CAD requires manipulation of genetic risk. The availability of microarrays of single-nucleotide polymorphisms enabling genome-wide association studies (GWAS) led to the discovery of 33 genetic risk variants for CAD....
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