Article
Francisella is sensitive to insect antimicrobial peptides.
Journal of innate immunity - 1 Jan 2013
Vonkavaara Malin, Pavel Shaikh Terkis Islam, Hölzl Kathrin, Nordfelth Roland, Sjöstedt Anders, Stöven Svenja
Abstract excerpt
Francisella tularensis causes the zoonotic disease tularemia. Arthropod vectors are important transmission routes for the disease, although it is not known how Francisella survives the efficient arthropod immune response. Here, we used Drosophila melanogaster as a model host for Francisella infections and investigated whether the bacteria are resistant to insect humoral immune responses, in particular to the...
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