Article
Altered development of white matter in youth at high familial risk for bipolar disorder: a diffusion tensor imaging study.
Journal of the American Academy of Child and Adolescent Psychiatry - 1 Dec 2010
Versace Amelia, Ladouceur Cecile D, Romero Soledad, Birmaher Boris, Axelson David A, Kupfer David J, Phillips Mary L
Abstract excerpt
OBJECTIVE: To study white matter (WM) development in youth at high familial risk for bipolar disorder (BD). WM alterations are reported in youth and adults with BD. WM undergoes important maturational changes in adolescence. Age-related changes in WM microstructure using diffusion tensor imaging with tract-based spatial statistics in healthy offspring having a parent with BD were compared with those in healthy...
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