Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Heterozygous loss of NF2 is an early molecular alteration in well-differentiated papillary mesothelioma of the peritoneum.

Cancer genetics - 1 Nov 2012

Nemoto Hiroshi, Tate Genshu, Kishimoto Koji, Saito Mitsuo, Shirahata Atsushi, Umemoto Takehiro, Matsubara Taketo, Goto Tetsuhiro, Mizukami Hiroki, Kigawa Gaku, Mitsuya Toshiyuki, Hibi Kenji

Abstract excerpt

Well-differentiated papillary mesothelioma of the peritoneum (WDPMP) is a rare disease, and many cases are either benign neoplasms or low-graded malignancies; however, a few cases show rapid progressive clinical courses. No effective therapy has yet been established for WDPMP, and the molecular b...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Mutational Analysis
Share to E2F1 Transcription Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fatal Outcome

Share to Genes, Neurofibromatosis 2

Share to Histocytochemistry

Share to Loss of Heterozygosity

Share to Mesothelioma

Share to Peritoneal Neoplasms

Source

Identifiers

PMID: 23036697
DOI: 10.1016/j.cancergen.2012.08.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-23036697-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Heterozygous loss of NF2 is an early molecular alteration in well-differentiated papillary mesothelioma of the peritoneum.PMID 23036697Read ↗

Well-Differentiated Papillary Mesothelioma of the Peritoneum Is Genetically Distinct from Malignant MesotheliomaSemantic proximity Read ↗

Well-differentiated papillary mesothelioma of the peritoneum is genetically defined by mutually exclusive mutations in TRAF7 and CDC42.Semantic proximity Read ↗

Identification of CD24 as a potential diagnostic and therapeutic target for malignant pleural mesotheliomaSemantic proximity Read ↗

Characterization of DNA hypermethylation in two cases of peritoneal mesothelioma.Semantic proximity Read ↗

Solid papillary mesothelial tumor.Semantic proximity Read ↗

First somatic mutation of E2F1 in a critical DNA binding residue discovered in well-differentiated papillary mesothelioma of the peritoneum.Semantic proximity Read ↗

Establishment and characterization of four malignant pleural mesothelioma cell lines from Japanese patientsSemantic proximity Read ↗

Molecular Analysis of a Patient With Neurofibromatosis 2 (NF2) and Peritoneal Malignant MesotheliomaSemantic proximity Read ↗

BAP1 loss is unusual in well-differentiated papillary mesothelioma and may predict development of malignant mesothelioma.Semantic proximity Read ↗

Frequent p16 inactivation by homozygous deletion or methylation is associated with a poor prognosis in Japanese patients with pleural mesotheliomaSemantic proximity Read ↗

A mouse model recapitulating molecular features of human mesothelioma.Semantic proximity Read ↗

Frequent mutations of NF2 and allelic loss from chromosome band 22q12 in malignant mesothelioma: evidence for a two-hit mechanism of NF2 inactivation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.