Article
Plasma based markers of [11C] PiB-PET brain amyloid burden.
PloS one - 1 Jan 2012
Kiddle Steven John, Thambisetty Madhav, Simmons Andrew, Riddoch-Contreras Joanna, Hye Abdul, Westman Eric, Pike Ian, Ward Malcolm, Johnston Caroline, Lupton Michelle Katharine, Lunnon Katie, Soininen Hilkka, Kloszewska Iwona, Tsolaki Magda, Vellas Bruno, Mecocci Patrizia, Lovestone Simon, Newhouse Stephen, Dobson Richard
Abstract excerpt
Changes in brain amyloid burden have been shown to relate to Alzheimer's disease pathology, and are believed to precede the development of cognitive decline. There is thus a need for inexpensive and non-invasive screening methods that are able to accurately estimate brain amyloid burden as a marker of Alzheimer's disease. One potential method would involve using demographic information and measurements on plasma...
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