Article
Genetic modifiers of chromatin acetylation antagonize the reprogramming of epi-polymorphisms.
PLoS genetics - 1 Sept 2012
Abraham Anne-Laure, Nagarajan Muniyandi, Veyrieras Jean-Baptiste, Bottin Hélène, Steinmetz Lars M, Yvert Gaël
Abstract excerpt
Natural populations are known to differ not only in DNA but also in their chromatin-associated epigenetic marks. When such inter-individual epigenomic differences (or "epi-polymorphisms") are observed, their stability is usually not known: they may or may not be reprogrammed over time or upon environmental changes. In addition, their origin may be purely epigenetic, or they may result from regulatory variation...
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