Article
Cadm1 is a metastasis susceptibility gene that suppresses metastasis by modifying tumor interaction with the cell-mediated immunity.
PLoS genetics - 1 Sept 2012
Faraji Farhoud, Pang Yanli, Walker Renard C, Nieves Borges Rosan, Yang Li, Hunter Kent W
Abstract excerpt
Metastasis is a complex process utilizing both tumor-cell-autonomous properties and host-derived factors, including cellular immunity. We have previously shown that germline polymorphisms can modify tumor cell metastatic capabilities through cell-autonomous mechanisms. However, how metastasis sus...
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