Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MIG-13 controls anteroposterior cell migration by interacting with UNC-71/ADM-1 and SRC-1 in Caenorhabditis elegans.

FEBS letters - 23 Mar 2012

Masuda Hitomi, Nakamura Kuniaki, Takata Nozomu, Itoh Bunsho, Hirose Takashi, Moribe Hiroki, Mekada Eisuke, Okada Masato

Abstract excerpt

The transmembrane protein MIG-13 is a key regulator required for anterior migration of neural cells in Caenorhabditis elegans, but the signaling mechanisms involved remain unknown. Here, we isolated a suppressor mutation in the unc-71/adm-1 gene, which rescued the AVM neuron migration defect in mig-13 mutants. Genetic analyses revealed that UNC-71 at least partly acts downstream of MIG-13 and has an inhibitory...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans
Share to Caenorhabditis elegans Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Movement

Share to Membrane Proteins

Share to Metalloendopeptidases

Share to Neurons

Share to Protein Kinases

Share to RNA Interference

Source

Identifiers

PMID: 22293500
DOI: 10.1016/j.febslet.2012.01.031

Genes

SRC
ADM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MIG-13 controls anteroposterior cell migration by interacting with UNC-71/ADM-1 and SRC-1 in Caenorhabditis elegans.PMID 22293500Read ↗

MIG-13 positions migrating cells along the anteroposterior body axis of C. elegans.Semantic proximity Read ↗

Abelson interactor-1 (ABI-1) interacts with MRL adaptor protein MIG-10 and is required in guided cell migrations and process outgrowth in C. elegans.Semantic proximity Read ↗

Interactions of UNC-34 Enabled with Rac GTPases and the NIK kinase MIG-15 in Caenorhabditis elegans axon pathfinding and neuronal migration.Semantic proximity Read ↗

MIG-10/lamellipodin and AGE-1/PI3K promote axon guidance and outgrowth in response to slit and netrin.Semantic proximity Read ↗

Mutations affecting symmetrical migration of distal tip cells in Caenorhabditis elegans.Semantic proximity Read ↗

The Caenorhabditis elegans matrix non-peptidase MNP-1 is required for neuronal cell migration and interacts with the Ror receptor tyrosine kinase CAM-1.Semantic proximity Read ↗

The UNC-73/Trio RhoGEF-2 domain is required in separate isoforms for the regulation of pharynx pumping and normal neurotransmission in C. elegans.Semantic proximity Read ↗

ENU-3 is a novel motor axon outgrowth and guidance protein in C. elegans.Semantic proximity Read ↗

Mutations affecting embryonic cell migrations in Caenorhabditis elegans.Semantic proximity Read ↗

An UNC-40 pathway directs postsynaptic membrane extension in Caenorhabditis elegans.Semantic proximity Read ↗

RACK-1 acts with Rac GTPase signaling and UNC-115/abLIM in Caenorhabditis elegans axon pathfinding and cell migration.Semantic proximity Read ↗

Genes necessary for C. elegans cell and growth cone migrations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.