Article
E-selectin rs5361 and FCGR2A rs1801274 variants were associated with increased risk of gastric cancer in a Chinese population.
Molecular carcinogenesis - 1 Aug 2012
Xia Hong-Zhen, Du Wei-Dong, Wu Qiang, Chen Gang, Zhou Yuan, Tang Xian-Fa, Tang Hua-Yang, Liu Yi, Yang Feng, Ruan Jian, Xu Song, Zuo Xian-Bo, Zhang Xue-Jun
Abstract excerpt
Host immune responses are critical steps for carcinogenesis. Single nucleotide polymorphisms (SNPs) in immunoregulatory genes may influence gastric cancer risk. We performed a genotyping analysis for immunoregulatory genes in 311 gastric cancer cases and 425 controls from a Chinese population. We found that there were significant differences of E-selectin variant rs5361 (A>C) and FCGR2A variant rs1801274 (T>C)...
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