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Article

Early retinoic acid deprivation in developing zebrafish results in microphthalmia.

Visual neuroscience - 1 Sept 2012

Le Hong-Gam T, Dowling John E, Cameron D Joshua

Abstract excerpt

Vitamin A deficiency causes impaired vision and blindness in millions of children around the world. Previous studies in zebrafish have demonstrated that retinoic acid (RA), the acid form of vitamin A, plays a vital role in early eye development. The objective of this study was to describe the effects of early RA deficiency by treating zebrafish with diethylaminobenzaldehyde (DEAB), a potent inhibitor of the...

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Identifiers

PMID: 23013828
DOI: 10.1017/S0952523812000296
PMCID: PMC3718850

Genes

ERG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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