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Article

Juvenile-onset visual impairment in zebrafish rlbp1b mutants highlights Müller glia contributions to cone vision.

Experimental eye research - 1 Oct 2026

Koutroumpa Ioanna S, Neuhauss Stephan C F

Abstract excerpt

Vision depends on the continuous recycling of the visual pigment chromophore 11-cis-retinal, which is converted by light into all-trans-retinal at the onset of the phototransduction cascade. Cellular retinaldehyde-binding protein 1 (CRALBP1) is a key component of both the canonical visual cycle in the retinal pigment epithelium (RPE) and the cone-specific recycling pathway mediated by Müller glia (MG) cells....

Read the complete abstract on PubMed

Topics

Animals
Zebrafish
Retinal Cone Photoreceptor Cells
Ependymoglial Cells
Electroretinography
Carrier Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Zebrafish Proteins

Dark Adaptation

Mutation

Vision Disorders

Retinal Pigment Epithelium

Retinal Rod Photoreceptor Cells

Source

Identifiers

PMID: 42431293
DOI: 10.1016/j.exer.2026.111163

Genes

RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 21 Oct 2026.

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