Poor prognosis of KRAS or BRAF mutant colorectal liver metastasis without microsatellite instability.

doi:10.1007/s00534-012-0531-9

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Article

Poor prognosis of KRAS or BRAF mutant colorectal liver metastasis without microsatellite instability.

Journal of hepato-biliary-pancreatic sciences - 1 Feb 2013

Umeda Yuzo, Nagasaka Takeshi, Mori Yoshiko, Sadamori Hiroshi, Sun Dong-Sheng, Shinoura Susumu, Yoshida Ryuich, Satoh Daisuke, Nobuoka Daisuke, Utsumi Masashi, Yoshida Kazuhiro, Yagi Takahito, Fujiwara Toshiyoshi

Abstract excerpt

BACKGROUND: The discovery of practical biomarkers is important to realize personalized medicine for patients with malignant neoplasias, including colorectal cancer (CRC). PURPOSE: The aim of this study was to determine reliable prognostic biomarkers by the analysis of patients with resectable col...

Topics

Aged
Biomarkers, Tumor
Colorectal Neoplasms
DNA Mutational Analysis
DNA, Neoplasm
Disease Progression
Female
Follow-Up Studies
Humans
Japan
Liver Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Microsatellite Instability

Mutation

Polymerase Chain Reaction

Prognosis

Proto-Oncogene Proteins

Proto-Oncogene Proteins B-raf

Source

Open in PubMed

Identifiers

PMID: 23010994
DOI: 10.1007/s00534-012-0531-9

Genes

BRAF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-23010994-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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