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Article

Poor prognosis of KRAS or BRAF mutant colorectal liver metastasis without microsatellite instability.

Journal of hepato-biliary-pancreatic sciences - 1 Feb 2013

Umeda Yuzo, Nagasaka Takeshi, Mori Yoshiko, Sadamori Hiroshi, Sun Dong-Sheng, Shinoura Susumu, Yoshida Ryuich, Satoh Daisuke, Nobuoka Daisuke, Utsumi Masashi, Yoshida Kazuhiro, Yagi Takahito, Fujiwara Toshiyoshi

Abstract excerpt

BACKGROUND: The discovery of practical biomarkers is important to realize personalized medicine for patients with malignant neoplasias, including colorectal cancer (CRC). PURPOSE: The aim of this study was to determine reliable prognostic biomarkers by the analysis of patients with resectable colorectal liver metastases (CRLM). METHODS: Genomic DNA was obtained from the CRLM tissues of a cohort of 126 patients...

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Identifiers

PMID: 23010994
DOI: 10.1007/s00534-012-0531-9

Genes

BRAF
KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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