Article
Cutaneous leukocytoclastic vasculitis due to Salmonella enteritidis in a child with interleukin-12 receptor beta-1 deficiency.
Pediatric dermatology - 1 Jan 2000
Filiz Serkan, Kocacik Uygun Dilara F, Verhard Els M, van Dissel Jaap T, Uygun Vedat, Bassorgun Cumhur, Bingol Aysen, Yegin Olcay, van de Vosse Esther
Abstract excerpt
Defects in the interleukin 12 (IL-12)/interferon gamma (IFN-γ) pathway result in Mendelian susceptibility to mycobacterial disease (MSMD). IL-12 receptor beta 1 (IL-12Rβ1) deficiency, the most common form of MSMD, is associated with weakly virulent mycobacteria and salmonella. Infections in patients with this deficiency are extraintestinal, or septicemic, recurrent infections with nontyphoid salmonellae. Here we...
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