Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Henoch-Schoenlein purpura-like lesions in IL12RB1 and IL12B defects-a multi-centric experience from India.

Clinical and experimental immunology - 6 Jan 2026

Sharma Yamini, Nadig Pallavi, Das Jhumki, Iyengar Vaishnavi, Loganathan Sathish Kumar, Chougule Akshaya, Gowri Vijaya, Taur Prasad, Pilania Rakesh, Dhaliwal Manpreet, Sharma Saniya, Chatterjee Debajyoti, Suri Deepti, Desai Mukesh, Singh Surjit, Vignesh Pandiarajan, Rawat Amit

Abstract excerpt

Mendelian susceptibility to mycobacterial disease (MSMD), caused by IL12RB1 or IL12B mutations, typically presents with intra-cellular infections such as BCG-adenitis or Salmonella. Rarely, patients with IL12RB1/IL12B defects can exhibit cutaneous manifestations such as Henoch-Schonlein purpura (HSP). This study aimed to evaluate such vasculitic manifestations in genetically confirmed cases with MSMD in India and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to IgA Vasculitis

Share to Immunoglobulin A

Share to Interleukin-12 Subunit p40

Share to Receptors, Interleukin-12

Source

Open in PubMed Open full text

Identifiers

PMID: 42366588
DOI: 10.1093/cei/uxag035
PMCID: PMC13367570

Genes

IL12B
IL12RB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Henoch-Schoenlein purpura-like lesions in IL12RB1 and IL12B defects-a multi-centric experience from India.PMID 42366588Read ↗

Disseminated Salmonellosis and cutaneous vasculitis in a child with IL12Rß1 deficiency – a case report & review of literature.Semantic proximity Read ↗

Clinical and Molecular Findings in Mendelian Susceptibility to Mycobacterial Diseases: Experience From India.Semantic proximity Read ↗

Genetic, immunologic, and clinical features of 830 patients with Mendelian susceptibility to mycobacterial diseases (MSMD): A systematic review.Semantic proximity Read ↗

Is there a crossroad between infections, genetics, and Henoch-Schönlein purpura?Semantic proximity Read ↗

Primary Immunodeficiencies in India: Molecular Diagnosis and the Role of Next-Generation Sequencing.Semantic proximity Read ↗

Wiskott Aldrich Syndrome: A Multi-Institutional Experience From India.Semantic proximity Read ↗

Characteristics of Talaromyces marneffei infection associated with inborn errors of immunitySemantic proximity Read ↗

Mendelian Susceptibility to Mycobacterial Disease (MSMD): Clinical and Genetic Features of 32 Iranian Patients.Semantic proximity Read ↗

Infectious diseases, autoimmunity and midline defect in a patient with a novel bi-allelic mutation in IL12RB1 gene.Semantic proximity Read ↗

Characteristics of Endemic Mycoses Talaromyces marneffei Infection Associated with Inborn Errors of Immunity.Semantic proximity Read ↗

Disseminated Salmonellosis in a child with IL12Rß1 deficiency – Case report and review of literature.Semantic proximity Read ↗

Inherited IL-12p40 deficiency: genetic, immunologic, and clinical features of 49 patients from 30 kindreds.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.