LP(a): Structure, Genetics, Associated Cardiovascular Risk, and Emerging Therapeutics

Abstract excerpt

Lipoprotein(a) [Lp(a)] is a molecule bound to apolipoprotein(a) with some similarity to low-density lipoprotein cholesterol (LDL-C), which has been found to be a risk factor for cardiovascular disease (CVD). Lp(a) appears to induce inflammation, atherogenesis, and thrombosis. Approximately 20% of the world's population has increased Lp(a) levels, determined predominantly by genetics. Current clinical practices...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Health Systems, Economic Evaluations, Quality of Life
• Share to Lipoproteins and Cardiovascular Health
• Share to Nuclear Receptors and Signaling