Article
Lack of association of OPRM1 genotype and smoking cessation.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco - 1 Mar 2013
Munafò Marcus R, Johnstone Elaine C, Aveyard Paul, Marteau Theresa
Abstract excerpt
INTRODUCTION: Previous studies have reported an association between μ-opioid receptor (OPRM1) genotype and smoking cessation, with some evidence that the strength of this association depends on dose of nicotine replacement therapy (NRT). We examined whether a single-nucleotide polymorphism in the OPRM1 gene is associated with cessation and whether this variant moderates the effects of higher doses of NRT on...
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