Article
Effect on adherence to nicotine replacement therapy of informing smokers their dose is determined by their genotype: a randomised controlled trial.
PloS one - 1 Jan 2012
Marteau Theresa M, Aveyard Paul, Munafò Marcus R, Prevost A Toby, Hollands Gareth J, Armstrong David, Sutton Stephen, Hill Chloe, Johnstone Elaine, Kinmonth Ann Louise
Abstract excerpt
BACKGROUND: The behavioural impact of pharmacogenomics is untested. We tested two hypotheses concerning the behavioural impact of informing smokers their oral dose of NRT is tailored to analysis of DNA. METHODS AND FINDINGS: We conducted an RCT with smokers in smoking cessation clinics (N = 633). In combination with NRT patch, participants were informed that their doses of oral NRT were based either on their...
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