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Article

Investigation of pseudogenes RHDΨ and RHD-CE-D hybrid gene in D-negative blood donors by the real time PCR method.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis - 1 Dec 2012

Szulman Alexandre, Nardozza Luciano Marcondes Machado, Barreto Jose Augusto, Araujo Júnior Edward, Moron Antonio Fernandes

Abstract excerpt

INTRODUCTION: The Rh system is the most polymorphic and immunogenic of all systems of blood groups. Currently more than 49 antigens were identified with five major antigens D, C, c, E, e. Knowledge of the molecular basis of the Rh system permitted the understanding of both the mechanism of Rh phe...

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Source

Identifiers

PMID: 22990002
DOI: 10.1016/j.transci.2012.07.007

Genes

RHD
RHCE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22990002-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigation of pseudogenes RHDΨ and RHD-CE-D hybrid gene in D-negative blood donors by the real time PCR method.PMID 22990002Read ↗

Presence of the RHD pseudogene and the hybrid RHD-CE-D(s) gene in Brazilians with the D-negative phenotype.Semantic proximity Read ↗

A convenient qualitative and quantitative method to investigate RHD-RHCE hybrid genes.Semantic proximity Read ↗

From the investigation of RHD-CE hybrid genes to the recognition of RHCE variants and RHD zygosity. Expanding the analysis by QMPSF in Brazilian donors and in patients with sickle cell disease.Semantic proximity Read ↗

The presence of an RHD pseudogene containing a 37 base pair duplication and a nonsense mutation in Africans with the Rh D-negative blood group phenotypeSemantic proximity Read ↗

Evaluation of the applicability and effectiveness of a molecular strategy for identifying weak D and DEL phenotype among D- blood donors of mixed origin exhibiting high frequency of RHD*Ψ.Semantic proximity Read ↗

Molecular basis of RhD-negative phenotype in North Indian blood donor population.Semantic proximity Read ↗

RHD and RHCE molecular analysis in weak D blood donors and in patients with Rh antibodies against their own corresponding Rh antigen.Semantic proximity Read ↗

[System RH: screening of partials D with RHD/RHCE hybrid gene].Semantic proximity Read ↗

First description of a D-CE-D hybrid gene on a weak D Type 2 molecular background.Semantic proximity Read ↗

The presence of an RHD pseudogene containing a 37 base pair duplication and a nonsense mutation in africans with the Rh D-negative blood group phenotype.Semantic proximity Read ↗

RHD gene polymorphisms in alloimmunized RhD-negative individuals with high rate of racial admixture.Semantic proximity Read ↗

Evidence of genetic diversity underlying Rh D-, weak D (Du), and partial D phenotypes as determined by multiplex polymerase chain reaction analysis of the RHD gene.Semantic proximity Read ↗

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