Article
RHD gene polymorphisms in alloimmunized RhD-negative individuals with high rate of racial admixture.
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis - 1 Feb 2013
Martin Fábio O, de Menezes Sidnéia S, Chiba Akemi K, Langhi Dante M, Nardozza Luciano M M, Chiattone Carlos S, Bordin José O
Abstract excerpt
BACKGROUND: The D-negative phenotype is the result of the total RHD gene deletion in almost all Caucasians, but it accounts for only about 20% in Africans and 70% in Asians. In Africans the RHDΨ that is one of the most important causes of the D-negative phenotype. We investigated the RHD polymorphisms in D-negative phenotype mixed Brazilians who have anti-D alloantibody. STUDY DESIGN AND METHODS: Blood samples...
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