Article
Molecular characterization and clinical presentation of HKαα and anti-HKαα alleles in southern Chinese subjects.
Clinical genetics - 1 May 2013
Shang X, Li Q, Cai R, Huang J, Wei X, Xu X
Abstract excerpt
The HKαα allele is a rearrangement occurring in the α-globin gene cluster containing both the -α(3.7) and ααα(anti4.2) unequal crossover junctions. The anti-HKαα allele is the reciprocal product containing both the -α(4.2) and ααα(anti3.7) unequal crossover junctions, which had been predicted but had not been detected previously. The phenotypic feature and population frequency of these two unusual alleles were...
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