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Article

Hb H Disease Caused by Multiple Mutations in the Polyadenylation Signal Site and - -SEA/αα.

Hemoglobin - 1 May 2017

Zhang Qiang, Fan Xin, Xu Mingli, Zhang Yijia, Xu Huiling, Wen Xiaojun, Zhou Wanjun

Abstract excerpt

Thalassemia is the most common monogenic disease, with the highest incidence in Guangxi Zhuang Autonomous Region, People's Republic of China (PRC). The blood test result was not consistent with α-globin gene testing in one of the patients during daily screening. It was confirmed that there were multiple mutations at the α2-globin gene polyadenylation (polyA) signal site: HBA2: c.*64(T>C), HBA2: c.*68(A>C), HBA2:...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28950779
DOI: 10.1080/03630269.2017.1366917

Genes

HBA2
SEA
HBA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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