Article
Identification of the -α(2.4) Deletion in One Family and in One Hb H Disease Patient in Guangxi, People's Republic of China.
Hemoglobin - 1 Jun 2016
Pang Wanrong, Sun Lei, Long Ju, Weng Xunjin, Ye Xuehe, Wang Junjie, Liao Yan, Tang Weijun, Fan Zuqian, Wu Suping, Song Chuanlu, Wei Xiaoying, Zhang Chenghong
Abstract excerpt
The 2.4 kb (or -α(2.4)) deletion in the α-globin gene cluster (NG_000006.1) is an α(+)-thalassemia (α(+)-thal) allele. The molecular basis of -α(2.4) is a deletion from 36860 to 39251 of the α-globin gene cluster. It was reported by three research groups in 2005, 2012 and 2014, respectively. In routine thalassemia screening studies by this research group, we found an individual with the -α(2.4)/αα genotype and an...
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