Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The frequency of HKαα allele in silent deletional α-thalassemia carriers in the Yulin region of southern China using the third-generation sequencing.

Gene - 30 Jul 2023

Ning Sisi, Qin Yunrong, Liang Yunning, Liang Yi, Xie Yuling, Lu Yinghong, Wei Guanghong, Xu Ruofan, Liu Yinyin, Li Jihui

Abstract excerpt

OBJECTIVES: α-thalassemia is relatively prevalent in Yulin Region in southern China. In order to accurately detect α-globin gene aberrations for genetic counseling, the prevalence of HKαα (Hong Kong αα) allele in this subpopulation of silent deletional α-thalassemia were examined. MATERIALS AND METHODS: A total of 1845 subjects were selected in Yulin Region from January 2021 to March 2021. Peripheral blood was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to alpha-Globins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to alpha-Thalassemia

Share to beta-Thalassemia

Share to Genotype

Share to Heterozygote

Share to Mutation

Source

Identifiers

PMID: 37217151
DOI: 10.1016/j.gene.2023.147505

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The frequency of HKαα allele in silent deletional α-thalassemia carriers in the Yulin region of southern China using the third-generation sequencing.PMID 37217151Read ↗

Accurate genotype diagnosis of Hong Kongαα thalassemia based on third-generation sequencingSemantic proximity Read ↗

Profiling structural variations of the α-globin gene cluster by the single molecule real-time sequencing: remarkable diversity of the spectrum with rare and novel variants identified in a large Chinese cohort.Semantic proximity Read ↗

Third-generation sequencing: A novel tool detects complex variants in the α-thalassemia gene.Semantic proximity Read ↗

Single‐Molecule Real‐Time Sequencing Reveals Hidden Diversity and Corrects Misdiagnosis in α‐ThalassemiaSemantic proximity Read ↗

Prevalence and genetic analysis of triplicated α-globin gene in Ganzhou region using high-throughput sequencingSemantic proximity Read ↗

Molecular spectrum and prevalence of thalassemia investigated by third-generation sequencing in the Dongguan region of Guangdong Province, Southern China.Semantic proximity Read ↗

Identification of a novel 10.3 kb deletion causing α0-thalassemia by third-generation sequencing: Pedigree analysis and genetic diagnosis.Semantic proximity Read ↗

Analysis of rare thalassemia genetic variants based on third-generation sequencing.Semantic proximity Read ↗

The spectrum of α- and β-thalassemia mutations in Yunnan Province of Southwestern China.Semantic proximity Read ↗

Analysis of genotypic distribution and rare variants of patients with α/β-thalassemia screened in one hospital in Beijing, China.Semantic proximity Read ↗

Analysis of Rare Thalassemia Genetic Variants Based on Third Generation SequencingSemantic proximity Read ↗

Prevalence and Molecular Spectrum of α- and β-Globin Gene Mutations in Hainan, ChinaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.