Article
KCNE3 T4A as the genetic basis of Brugada-pattern electrocardiogram.
Circulation journal : official journal of the Japanese Circulation Society - 1 Jan 2012
Nakajima Tadashi, Wu Jie, Kaneko Yoshiaki, Ashihara Takashi, Ohno Seiko, Irie Tadanobu, Ding Wei-Guang, Matsuura Hiroshi, Kurabayashi Masahiko, Horie Minoru
Abstract excerpt
BACKGROUND: Brugada syndrome (BrS) is genetically heterogeneous. In Japanese BrS patients, except for SCN5A and KCNE5, mutations in the responsible genes have not yet been identified, and therefore the genetic heterogeneity remains poorly elucidated. METHODS AND RESULTS: Forty consecutive patients with Brugada-pattern electrocardiogram (ECG) underwent comprehensive genetic analysis of BrS-causing genes including...
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