Article
Analysis of immunogenicity of different protein groups from malaria parasite Plasmodium falciparum.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2012
Krzyczmonik Katarzyna, Świtnicki Michał, Kaczanowski Szymon
Abstract excerpt
It was observed that pressure of host immune system leads to diversifying selection (which can be measured in terms of pN/pS ratio). In this research we checked whether Plasmodium falciparum proteins containing experimentally evident epitopes from the IEDB database are subject to diversifying selection. We also investigated which life stage of this parasite and which proteins are subject to the strongest immune...
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