Article
Parental age and seasonal variation in the births of children with sporadic retinoblastoma: a mutation-epidemiologic study.
Human genetics - 1 Jan 1990
Matsunaga E, Minoda K, Sasaki M S
Abstract excerpt
Statistical analysis of parental age data from 225 sporadic cases of bilateral retinoblastoma, plus ten sporadic cases of chromosome deletion or translocation involving 13q14 that was identified as of paternal origin, revealed no evidence of paternal or maternal age effect. Parental exposure to ionizing radiation or chemical mutagens, the effect of which is accumulated with advancing age, does not seem to play a...
Topics
- Adolescent
- Adult
- Eye Neoplasms
- Female
- Humans
- Infant, Newborn
- Male
- Middle Aged
- Mutation
- Parents
- Retinoblastoma
- Seasons