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Article

Parental age and retinoblastoma-a retrospective study of demographic data and genetic analysis.

Eye (London, England) - 1 Jan 2022

Tanwar Meghana, Balaji Sekaran, Vanniarajan Ayyasamy, Kim Usha, Chowdhury Gunja

Abstract excerpt

OBJECTIVE: To determine the association between the parental age gap and the absolute parental age with the risk of retinoblastoma (RB) development in an offspring. METHODS: RB individuals diagnosed between March 2013 and December 2019 in a single tertiary eye care centre were included. We recorded the demographic data, parental age and RB1 gene mutation status in the patient's tumour, blood and the parental...

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Identifiers

PMID: 34799705
DOI: 10.1038/s41433-021-01771-z
PMCID: PMC8727630

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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