Article
Participation of 47C>T SNP (Ala-9Val polymorphism) of the SOD2 gene in the intracellular environment of human peripheral blood mononuclear cells with and without lipopolysaccharides.
Molecular and cellular biochemistry - 1 Jan 2013
Paludo Francis Jackson O, Simões-Pires André, Alho Clarice S, Gelain Daniel Pens, Moreira José Cláudio F
Abstract excerpt
The outcome of sepsis occurs due to influence of environmental and genetic factors besides genes variants whose expression support its outcome or not. Oxidative stress is associated to the pathogenicity of sepsis, occurring when there is a reactive species overproduction associated with inflammation. The aim of this study was to characterize the cellular redox status of human peripheral blood mononuclear cells...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.