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Article

New insights into Dok-4 PTB domain structure and function.

Biochemical and biophysical research communications - 12 Oct 2012

Hooker Erika, Baldwin Cindy, Lemay Serge

Abstract excerpt

The seven members of the Dok adapter protein family share a highly conserved phosphotyrosine-binding (PTB) domain. In the case of Dok-1, 2 and 3, the PTB domain binds to the lipid phosphatase Ship1, a key component of their inhibitory signaling mechanisms in immune cells. In contrast to most othe...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases

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Source

Identifiers

PMID: 22982678
DOI: 10.1016/j.bbrc.2012.08.148

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22982678-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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