Article
Effect of modulating macrophage phenotype on peripheral nerve repair.
Biomaterials - 1 Dec 2012
Mokarram Nassir, Merchant Alishah, Mukhatyar Vivek, Patel Gaurangkumar, Bellamkonda Ravi V
Abstract excerpt
Peripheral nerve repair across long gaps remains clinically challenging despite progress made with autograft transplantation. While scaffolds that present trophic factors and extracellular matrix molecules have been designed, matching the performance of autograft-induced repair has been challenging. In this study, we explored the effect of cytokine mediated 'biasing' of macrophage phenotypes on Schwann cell (SC)...
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