Article
Stochastic modeling of cellular networks.
Methods in cell biology - 1 Jan 2012
Stewart-Ornstein Jacob, El-Samad Hana
Abstract excerpt
Noise and stochasticity are fundamental to biology because they derive from the nature of biochemical reactions. Thermal motions of molecules translate into randomness in the sequence and timing of reactions, which leads to cell-cell variability ("noise") in mRNA and protein levels even in clonal populations of genetically identical cells. This is a quantitative phenotype that has important functional...
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