Article
Targeting basal-like breast cancers.
Current drug targets - 1 Nov 2012
Dey Nandini, Smith Brian R, Leyland-Jones B
Abstract excerpt
Basal-like breast tumors and triple negative breast tumors are high-risk breast cancers that typically carry the poorest prognoses compared with HR (Hormone Receptor)-positive tumors and HER2 (Human Epidermal growth factor Receptor 2)-amplified tumors for known therapies. These subsets of breast cancers exhibit aggressive clinical behavior, pushing margins of invasion, poor clinical outcome, and derive limited...
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