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Article

Coronin 3 promotes gastric cancer metastasis via the up-regulation of MMP-9 and cathepsin K

14 Sept 2012

Abstract excerpt

BACKGROUND: Coronins are a family of highly evolutionary conserved proteins reportedly involved in the regulation of actin cytoskeletal dynamics, although only coronin 3 has been shown to be related to cancer cell migration. In glioblastoma cells, the knockdown of coronin 3 inhibits cell proliferation and invasion. Coronin 3 is also associated with the aggression and metastasis of hepatocellular carcinoma. In...

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PMID: 22974233
DOI: 10.1186/1476-4598-11-67

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