Article
A miR-29c binding site genetic variant in the 3'-untranslated region of LAMTOR3 gene is associated with gastric cancer risk.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Feb 2015
Song Peng, Wang Weizhi, Tao Guoquan, Chu Haiyan, Wang Meilin, Wu Dongmei, Tong Na, Gong Weida, Zhou Jianwei, Zhang Zhengdong, Wang Baolin, Zhu Haixia, Zhao Qinghong
Abstract excerpt
Single nucleotide polymorphisms (SNPs) in the 3'-untranslated regions (UTRs) targeted by putative mircoRNAs (miRNAs) could influence the susceptibility of cancer. Recently, miR-29c has been reported to be down-regulated in gastric cancer (GC) and serve as a tumor suppressor that regulated tumor progression. The present study was aimed at investigating whether the miR-29c binding site SNPs within the 3'-UTRs of...
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