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Whole genome expression profiling based on paraffin embedded tissue can be used to classify diffuse large <scp>B</scp>‐cell lymphoma and predict clinical outcome

13 Sept 2012

Abstract excerpt

This study tested the validity of whole-genome expression profiling (GEP) using RNA from formalin-fixed, paraffin-embedded (FFPE) tissue to sub-classify Diffuse Large B-cell Lymphoma (DLBCL), in a population based cohort of 172 patients. GEP was performed using Illumina Whole Genome cDNA-mediated Annealing, Selection, extension & Ligation, and tumours were classified into germinal centre (GCB), activated B-cell...

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PMID: 22970711
DOI: 10.1111/bjh.12045

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