Article
Autoimmune diseases: MIF as a therapeutic target.
Expert opinion on therapeutic targets - 1 Mar 2010
Greven Dorothee, Leng Lin, Bucala Richard
Abstract excerpt
IMPORTANCE OF THE FIELD: Autoimmune inflammatory diseases occur commonly in developed countries. The treatment of these diseases is usually non-curative and is aimed at suppressing inflammatory end-organ damage. Macrophage migration inhibitory factor (MIF) is a multipotent cytokine that has been implicated in the pathogenesis of numerous autoimmune inflammatory disorders. The selective targeting of MIF with...
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