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Article

Bmi-1 promotes the aggressiveness of glioma via activating the NF-kappaB/MMP-9 signaling pathway.

BMC cancer - 11 Sept 2012

Jiang Lili, Wu Jueheng, Yang Yi, Liu Liping, Song Libing, Li Jun, Li Mengfeng

Abstract excerpt

BACKGROUND: The prognosis of human glioma is poor, and the highly invasive nature of the disease represents a major impediment to current therapeutic modalities. The oncoprotein B-cell-specific Moloney murine leukemia virus integration site 1 protein (Bmi-1) has been linked to the development and progression of glioma; however, the biological role of Bmi-1 in the invasion of glioma remains unclear. METHODS: A172...

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Source

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Identifiers

PMID: 22967049
DOI: 10.1186/1471-2407-12-406
PMCID: PMC3502583

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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