Article
Gene signature critical to cancer phenotype as a paradigm for anticancer drug discovery.
Oncogene - 15 Aug 2013
Sampson E R, McMurray H R, Hassane D C, Newman L, Salzman P, Jordan C T, Land H
Abstract excerpt
Malignant cell transformation commonly results in the deregulation of thousands of cellular genes, an observation that suggests a complex biological process and an inherently challenging scenario for the development of effective cancer interventions. To better define the genes/pathways essential...
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