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Article

Coupled mutation finder: a new entropy-based method quantifying phylogenetic noise for the detection of compensatory mutations.

BMC bioinformatics - 11 Sept 2012

Gültas Mehmet, Haubrock Martin, Tüysüz Nesrin, Waack Stephan

Abstract excerpt

BACKGROUND: The detection of significant compensatory mutation signals in multiple sequence alignments (MSAs) is often complicated by noise. A challenging problem in bioinformatics is remains the separation of significant signals between two or more non-conserved residue sites from the phylogenet...

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Identifiers

PMID: 22963049
DOI: 10.1186/1471-2105-13-225
PMCID: PMC3577461

Genes

EGFR
GCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22963049-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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