Article
From phenotype to genotype: an association study of longitudinal phenotypic markers to Alzheimer's disease relevant SNPs.
Bioinformatics (Oxford, England) - 15 Sept 2012
Wang Hua, Nie Feiping, Huang Heng, Yan Jingwen, Kim Sungeun, Nho Kwangsik, Risacher Shannon L, Saykin Andrew J, Shen Li
Abstract excerpt
MOTIVATION: Imaging genetic studies typically focus on identifying single-nucleotide polymorphism (SNP) markers associated with imaging phenotypes. Few studies perform regression of SNP values on phenotypic measures for examining how the SNP values change when phenotypic measures are varied. This alternative approach may have a potential to help us discover important imaging genetic associations from a different...
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