Article
Co-sparse reduced-rank regression for association analysis between imaging phenotypes and genetic variants.
Bioinformatics (Oxford, England) - 29 Jan 2021
Wen Canhong, Ba Hailong, Pan Wenliang, Huang Meiyan
Abstract excerpt
MOTIVATION: The association analysis between genetic variants and imaging phenotypes must be carried out to understand the inherited neuropsychiatric disorders via imaging genetic studies. Given the high dimensionality in imaging and genetic data, traditional methods based on massive univariate regression entail large computational cost and disregard many-to-many correlations between phenotypes and genetic...
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