Article
Directional evolution of Chlamydia trachomatis towards niche-specific adaptation.
Journal of bacteriology - 1 Nov 2012
Borges Vítor, Nunes Alexandra, Ferreira Rita, Borrego Maria J, Gomes João P
Abstract excerpt
On behalf of the host-pathogen "arms race," a cutting-edge approach for elucidating genotype-phenotype relationships relies on the identification of positively selected loci involved in pathoadaptation. We studied the obligate intracellular bacterium Chlamydia trachomatis, for which same-species strains display a nearly identical core and pan genome, while presenting a wide range of tissue tropism and ecological...
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