Back to search

Article

Patterns of within-host spread of <i>Chlamydia trachomatis</i> between vagina, endocervix and rectum revealed by comparative genomic analysis

2023-01-26

Abstract excerpt

Chlamydia trachomatis , a gram-negative obligate intracellular bacterium, commonly causes sexually transmitted infections (STIs). Little is known about C. trachomatis transmission within the host, which is important for understanding disease epidemiology and progression. We used RNA-bait enrichment and whole-genome sequencing to compare rectal, vaginal and endocervical samples collected at the same time from 26 s...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
df560362-f4b6-50ef-9a3a-cd8de740fc60
DOI
10.1101/2023.01.25.525576
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Patterns of within-host spread of <i>Chlamydia trachomatis</i> between vagina, endocervix and rectum revealed by comparative genomic analysisDOI 10.1101/2023.01.25.525576
Whole-Genome Enrichment and Sequencing of <i>Chlamydia trachomatis</i> Directly from Patient Clinical Vaginal and Rectal SwabsSemantic proximity
Metagenomic Shotgun Sequencing of Endocervical, Vaginal, and Rectal Samples among Fijian Women with and without Chlamydia trachomatis Reveals Disparate Microbial Populations and Function across Anatomic Sites: a Pilot StudySemantic proximity
Genome Sequencing of Recent Clinical <i>Chlamydia trachomatis</i> Strains Identifies Loci Associated with Tissue Tropism and Regions of Apparent RecombinationSemantic proximity
Evolution of Chlamydia trachomatisSemantic proximity
Evolution, phylogeny, and molecular epidemiology of Chlamydia.Semantic proximity
Whole-genome enrichment and sequencing of Chlamydia trachomatisdirectly from clinical samplesSemantic proximity
The Hidden Genomics of Chlamydia trachomatis.Semantic proximity
Chlamydia trachomatis diversity viewed as a tissue-specific coevolutionary arms race.Semantic proximity
The unique microbial diversity, community composition and networks of Pacific Islander endocervical and vaginal microbiomes in the presence or absence of <i>Chlamydia trachomatis</i> infection using metagenomic shotgun sequencingSemantic proximity
The challenge of sequencing <i>Chlamydia trachomatis</i> and other bacterial sexually transmitted infections genomes directly from clinical swabs: the optimum solutionSemantic proximity
Chlamydia trachomatis and Chlamydia pneumoniae Interaction with the Host: Latest Advances and Future ProspectiveSemantic proximity
<i>Chlamydia trachomatis</i> genomes from rectal samples: description of new clade comprising <i>ompA</i> -genotype L4 from ArgentinaSemantic proximity
Select a neighboring publication to make it the new centre.