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Article

Influence of polymorphisms and TNF and IL1β serum concentration on the infliximab response in Crohn's disease and ulcerative colitis.

European journal of clinical pharmacology - 1 Mar 2013

Lacruz-Guzmán Diana, Torres-Moreno Daniel, Pedrero Francisco, Romero-Cara Patricia, García-Tercero Iván, Trujillo-Santos Javier, Conesa-Zamora Pablo

Abstract excerpt

AIM: Inflammatory bowel diseases (IBD), such as Crohn's disease (CD) and ulcerative colitis (UC), are partially attributable to an increased secretion of proinflamatory cytokines, such as tumour necrosis factor (TNF) and interleukin-1β (IL1β), which play essential roles in the disease pathogenesi...

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Source

Identifiers

PMID: 22960943
DOI: 10.1007/s00228-012-1389-0

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22960943-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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