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Article

Increased risk of venous thromboembolism is associated with genetic variation in heme oxygenase-1 in Blacks.

Thrombosis research - 1 Dec 2012

Bean Christopher J, Boulet Sheree L, Ellingsen Dorothy, Trau Heidi, Ghaji Nafisa, Hooper W Craig, Austin Harland

Abstract excerpt

BACKGROUND: Venous thromboembolism (VTE) affects as many as 1 in 1000 individuals in the United States. Although Blacks are disproportionately affected by VTE, few genetic risk factors have been identified in this population. The inducible heme oxygenase-1 (HMOX1) gene encodes a key cytoprotective enzyme with anti-inflammatory, antioxidant and anticoagulant activity acting in the vascular system. A (GT)(n)...

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Source

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Identifiers

PMID: 22959128
DOI: 10.1016/j.thromres.2012.08.300
PMCID: PMC4388034

Genes

HMOX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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