Article
Genetic variation in heme oxygenase 1 (HMOX1) and the risk of recurrent venous thromboembolism.
Journal of vascular surgery - 1 Mar 2008
Mustafa Stefan, Weltermann Ansgar, Fritsche Robert, Marsik Claudia, Wagner Oswald, Kyrle Paul A, Eichinger Sabine
Abstract excerpt
BACKGROUND/OBJECTIVE: Products of heme oxygenase 1 (HO1) possess antithrombotic properties, and impairment of HO1 activity may contribute to thrombus formation. Transcriptional activity of long GT-repeat alleles in HO1 gene (HMOX1) is lower as compared with short alleles. We hypothesize that thes...
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