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Article

Genetic variation in heme oxygenase 1 (HMOX1) and the risk of recurrent venous thromboembolism.

Journal of vascular surgery - 1 Mar 2008

Mustafa Stefan, Weltermann Ansgar, Fritsche Robert, Marsik Claudia, Wagner Oswald, Kyrle Paul A, Eichinger Sabine

Abstract excerpt

BACKGROUND/OBJECTIVE: Products of heme oxygenase 1 (HO1) possess antithrombotic properties, and impairment of HO1 activity may contribute to thrombus formation. Transcriptional activity of long GT-repeat alleles in HO1 gene (HMOX1) is lower as compared with short alleles. We hypothesize that these long alleles are associated with decreased HO1 anticoagulant activity and, thus, an increased risk of thrombosis.....

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Source

Identifiers

PMID: 18201862
DOI: 10.1016/j.jvs.2007.09.060

Genes

HMOX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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