Article
Conversion of the C4d.2 serologic allotype of murine complement component C4 to the C4d.1 allotype by site-specific mutagenesis.
Journal of immunology (Baltimore, Md. : 1950) - 15 Jan 1990
Mathias P, Shreffler D C, Cooper N R, Ogata R T
Abstract excerpt
C4d.1 and C4d.2 are serologically defined allotypes of murine complement component C4. Previous studies in Shreffler's laboratory have shown that the structural difference between the two allotypes lies within a single tryptic peptide of the C4 alpha-chain and that the sequences of this fragment...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Complement C4
- Complement C4b
- DNA
- DNA Mutational Analysis
- Mice
- Molecular Sequence Data
- Peptide Fragments
- Precipitin Tests