Article
The mouse factor H allotypes with multiple amino acid replacement, H.1 and H.2 show indistinguishable co-factor activity for factor I.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Jan 2000
Natsuume-Sakai S, Okada M, Seya T, Nonaka M, Harada Y, Moriwaki K
Abstract excerpt
The authors report the functional analysis of the purified mouse factor H allotypes H.1 and H.2, which were clearly distinguished from each other by an immunodiffusion test. Both allotypes acted as a co-factor for factor I in cleaving mouse C3b and we found no significant difference between their...
Topics
- Alleles
- Animals
- Complement C3b Inactivator Proteins
- Complement Factor H
- Complement Factor I
- Mice
- Molecular Weight
- Serine Endopeptidases
- Transfection