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Article

Relationship between within-host fitness and virulence in the vesicular stomatitis virus: correlation with partial decoupling.

Journal of virology - 1 Nov 2012

Furió Victoria, Garijo Raquel, Durán María, Moya Andrés, Bell John C, Sanjuán Rafael

Abstract excerpt

Given the parasitic nature of viruses, it is sometimes assumed that rates of viral replication and dissemination within hosts (within-host fitness) correlate with virulence. However, there is currently little empirical evidence supporting this principle. To test this, we quantified the fitness and virulence of 21 single- or double-nucleotide mutants of the vesicular stomatitis virus in baby hamster kidney cells...

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Source

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Identifiers

PMID: 22951843
DOI: 10.1128/JVI.00755-12
PMCID: PMC3486475

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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