Article
In vivo fitness and virulence of a drug-resistant herpes simplex virus 1 mutant.
The Journal of general virology - 1 May 2007
Pesola Jean M, Coen Donald M
Abstract excerpt
Two important issues regarding a virus mutant that is resistant to an antiviral drug are its ability to replicate in animal hosts (in vivo fitness) relative to other genetic variants, including wild type, and its ability to cause disease. These issues have been investigated for a herpes simplex v...
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